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UpSET recruits HDAC complexes and restricts chromatin accessibility and histone acetylation at promoter regions

Developmental gene expression results from the orchestrated interplay between genetic and epigenetic mechanisms. Here we describe upSET, a transcriptional regulator encoding a SET domain-containing protein recruited to active and inducible genes in Drosophila. However, unlike other Drosophila SET pr...

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Autori principali: Rincon-Arano, Hector, Halow, Jessica, Delrow, Jeffrey J., Parkhurst, Susan M., Groudine, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518625/
https://ncbi.nlm.nih.gov/pubmed/23177352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.11.009
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