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UpSET-ing the balance: Modulating open chromatin features in metazoan genomes

Appropriate gene expression relies on the sophisticated interplay between genetic and epigenetic factors. Histone acetylation and an open chromatin configuration are key features of transcribed regions and are mainly present around active promoters. Our recent identification of the SET-domain contai...

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Detalhes bibliográficos
Main Authors: Rincon-Arano, Hector, Parkhurst, Susan M, Groudine, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049847/
https://ncbi.nlm.nih.gov/pubmed/23649046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/fly.24732
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