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Water Soluble Acyloxy Nitroso Compounds: HNO Release and Reactions with Heme and Thiol Containing Proteins

Nitroxyl (HNO) has gained interest as a potential treatment of congestive heart failure through the ability of the HNO donor, Angeli’s salt (AS), to evoke positive inotropic effects in canine cardiac muscle. The release of nitrite during decomposition limits the use of AS requiring other HNO sources...

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Detalhes bibliográficos
Main Authors: DuMond, Jenna F., Wright, Marcus W., King, S. Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518590/
https://ncbi.nlm.nih.gov/pubmed/23083700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2012.07.023
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