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A single residue change leads to a hydroxylated product from the class II diterpene cyclization catalyzed by abietadiene synthase
[Image: see text] Class II diterpene cyclases catalyze bicyclization of geranylgeranyl diphosphate. While this reaction typically is terminated via methyl deprotonation to yield copalyl diphosphate, in rare cases hydroxylated bicycles are produced instead. Abietadiene synthase is a bifunctional dite...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518578/ https://ncbi.nlm.nih.gov/pubmed/23167845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol3026022 |
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