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Following evolution's lead to a single residue switch for diterpene synthase product outcome

There have been few insights into the biochemical origins of natural product biosynthesis from primary metabolism. Of particular interest are terpene synthases, which often mediate the committed step in particular biosynthetic pathways so that alteration of their product outcome is a key step in the...

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Autores principales: Xu, Meimei, Wilderman, P. Ross, Peters, Reuben J.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855280/
https://ncbi.nlm.nih.gov/pubmed/17456599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611454104
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