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Insights into Diterpene Cyclization from Structure of Bifunctional Abietadiene Synthase from Abies grandis
Abietadiene synthase from Abies grandis (AgAS) is a model system for diterpene synthase activity, catalyzing class I (ionization-initiated) and class II (protonation-initiated) cyclization reactions. Reported here is the crystal structure of AgAS at 2.3 Å resolution and molecular dynamics simulation...
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| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Biochemistry and Molecular Biology
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3307272/ https://ncbi.nlm.nih.gov/pubmed/22219188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.337592 |
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