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Studying the role of the immune system on the antitumor activity of a Hedgehog inhibitor against murine osteosarcoma
Recent evidence demonstrates that the efficacy of conventional anticancer therapies including chemotherapy requires a functional immune system. Here, we addressed the possibility that the antitumor effect of a selective Smoothened antagonist and Hedgehog (Hh) pathway inhibitor (LDE225), a promising...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Landes Bioscience
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518504/ https://ncbi.nlm.nih.gov/pubmed/23243595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21680 |
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