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Depletion of phagocytic myeloid cells triggers spontaneous T cell- and NK cell-dependent antitumor activity

Depletion of tumor associated macrophages and inhibition of tumor angiogenesis have been invoked as the principle mechanisms underlying the antitumor activity of liposomal clodronate (LC). However, previous studies have not examined the effects of LC on systemic antitumor immunity. Here, we used mou...

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Библиографические подробности
Главные авторы: Guth, Amanda M., Hafeman, Scott D., Dow, Steven W.
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518497/
https://ncbi.nlm.nih.gov/pubmed/23243588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21317
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