Toll-like receptor adaptor signaling molecule MyD88 on intervertebral disk homeostasis: In vitro, ex vivo studies

MyD88 is an adapter protein that links toll-like receptors (TLRs) and Interleukin-1 receptors (IL-1Rs) with downstream signaling molecules. The MyD88 has been found to be an essential mediator in the development of osteoarthritis in articular cartilage. However, the role of the MyD88 pathway has yet...

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Main Authors: Ellman, Michael B., Kim, Jae-Sung, An, Howard S., Chen, Di, KC, Ranjan, An, Jennifer, Dittakavi, Teju, van Wijnen, Andre J., Cs-Szabo, Gabriella, Li, Xin, Xiao, Guozhi, An, Steven, Kim, Su-Gwan, Im, Hee-Jeong
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518428/
https://ncbi.nlm.nih.gov/pubmed/22692007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2012.06.004
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