Llwytho...

Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation

Pluripotent embryonic stem cells (ESCs) have a shortened cell cycle that enables their rapid proliferation. The ESC-specific miR-290 and miR-302 microRNA families promote proliferation whereas let-7 microRNAs inhibit self-renewal and promote cell differentiation. Lin28 suppresses let-7 expression in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chang, Hao-Ming, Martinez, Natalia J., Thornton, James E., Gregory, Richard I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518406/
https://ncbi.nlm.nih.gov/pubmed/22735451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1909
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