Regulation of Neuronal Excitability by Interaction of Fragile X Mental Retardation Protein with Slack Potassium Channels

Loss of the RNA-binding protein fragile X mental retardation protein (FMRP) represents the most common form of inherited intellectual disability. Studies with heterologous expression systems indicate that FMRP interacts directly with Slack Na(+)-activated K(+) channels (K(Na)), producing an enhancem...

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Huvudupphovsmän: Zhang, Yalan, Brown, Maile R., Hyland, Callen, Chen, Yi, Kronengold, Jack, Fleming, Matthew R., Kohn, Andrea B., Moroz, Leonid L., Kaczmarek, Leonard K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2012
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518385/
https://ncbi.nlm.nih.gov/pubmed/23115170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2162-12.2012
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