Fragile X Mental Retardation Protein Is Required for Rapid Experience-Dependent Regulation of the Potassium Channel Kv3.1b

Fragile X mental retardation protein (FMRP) is an RNA-binding protein that regulates synaptic plasticity by repressing translation of specific mRNAs. We found that FMRP binds mRNA encoding the voltage-gated potassium channel Kv3.1b in brainstem synaptosomes. To explore the regulation of Kv3.1b by FM...

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Hauptverfasser: Strumbos, John G., Brown, Maile R., Kronengold, Jack, Polley, Daniel B., Kaczmarek, Leonard K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2010
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485078/
https://ncbi.nlm.nih.gov/pubmed/20685971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1125-10.2010
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