Differential baseline expression and angiotensin II–stimulation of leukemia-associated RhoGEF in vascular smooth muscle cells of spontaneously hypertensive rats

PURPOSE: Studies to explore angiotensin II (Ang II) and its downstream signaling pathways via Rho guanine nucleotide exchange factors (RhoGEFs) and RhoA signaling are crucial to understanding the mechanisms of smooth muscle contraction leading to hypertension. This study aimed to investigate the Ang...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chiu, Wei-Chiao, Juang, Jyh-ming, Chang, Shen-nan, Wu, Cho-kai, Tsai, Chia-ti, Tseng, Chuen-den, Tseng, Yung-zu, Su, Ming-Jai, Chiang, Fu-tien
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2012
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518287/
https://ncbi.nlm.nih.gov/pubmed/23233801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S36700
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