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Differential baseline expression and angiotensin II–stimulation of leukemia-associated RhoGEF in vascular smooth muscle cells of spontaneously hypertensive rats

PURPOSE: Studies to explore angiotensin II (Ang II) and its downstream signaling pathways via Rho guanine nucleotide exchange factors (RhoGEFs) and RhoA signaling are crucial to understanding the mechanisms of smooth muscle contraction leading to hypertension. This study aimed to investigate the Ang...

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Autors principals: Chiu, Wei-Chiao, Juang, Jyh-ming, Chang, Shen-nan, Wu, Cho-kai, Tsai, Chia-ti, Tseng, Chuen-den, Tseng, Yung-zu, Su, Ming-Jai, Chiang, Fu-tien
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518287/
https://ncbi.nlm.nih.gov/pubmed/23233801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S36700
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