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Analysis of SRC Oncogenic Signaling in Colorectal Cancer by Stable Isotope Labeling with Heavy Amino Acids in Mouse Xenografts

The non-receptor tyrosine kinase SRC is frequently deregulated in human colorectal cancer (CRC), and SRC increased activity has been associated with poor clinical outcomes. In nude mice engrafted with human CRC cells, SRC over-expression favors tumor growth and is accompanied by a robust increase in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sirvent, Audrey, Vigy, Oana, Orsetti, Beatrice, Urbach, Serge, Roche, Serge
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518126/
https://ncbi.nlm.nih.gov/pubmed/23023324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.018168
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