A Phase II Study of O6-Benzylguanine and Temozolomide in Pediatric Patients with Recurrent or Progressive High Grade Gliomas and Brainstem Gliomas: A Pediatric Brain Tumor Consortium Study

PURPOSE: To estimate the sustained (≥8 weeks) objective response rate in pediatric patients with recurrent or progressive high-grade gliomas (HGG, Stratum A) or brainstem gliomas (BSG, Stratum B) treated with the combination of O6-benzylguanine (O6BG) and temozolomide® (TMZ). PATIENTS AND METHODS: P...

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Detalhes bibliográficos
Main Authors: Warren, Katherine E., Gururangan, Sri, Geyer, J. Russell, McLendon, Roger E., Poussaint, Tina Young, Wallace, Dana, Balis, Frank M., Berg, Stacey L., Packer, Roger J., Goldman, Stewart, Minturn, Jane E., Pollack, Ian F., Boyett, James M., Kun, Larry E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518022/
https://ncbi.nlm.nih.gov/pubmed/21968943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-011-0709-z
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