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Defining new roles for TBX3 in human ESCs: TBX3 promotes human embryonic stem cell proliferation and neuroepithelial differentiation in a differentiation stage-dependent manner

T-box 3 (Tbx3) is a member of the T-box family of genes. Mutations that result in the haploinsufficiency of TBX3 cause Ulnar Mammary Syndrome (UMS) in humans characterized by mammary gland hypoplasia as well as other congenital defects. In mice, homozygous mutations are embryonic lethal, suggesting...

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Detalhes bibliográficos
Main Authors: Esmailpour, Taraneh, Huang, Taosheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517731/
https://ncbi.nlm.nih.gov/pubmed/22865636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1187
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