TBX3 over-expression causes mammary gland hyperplasia and increases mammary stem-like cells in an inducible transgenic mouse model

BACKGROUND: The T-box transcription factor TBX3 is necessary for early embryonic development and for the normal development of the mammary gland. Homozygous mutations, in mice, are embryonic lethal while heterozygous mutations result in perturbed mammary gland development. In humans, mutations that...

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Autors principals: Liu, Jing, Esmailpour, Taraneh, Shang, Xiying, Gulsen, Gultekin, Liu, Andy, Huang, Taosheng
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217876/
https://ncbi.nlm.nih.gov/pubmed/22039763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-11-65
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