The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation

BAF complexes are composed of different subunits with varying functional and developmental roles, although many subunits have not been examined in depth. Here we show that the Baf45 subunit Dpf2 maintains pluripotency and ESC differentiation potential. Dpf2 co-occupies enhancers with Oct4, Sox2, p30...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Zhang, Wensheng, Chronis, Constantinos, Chen, Xi, Zhang, Heyao, Spalinskas, Rapolas, Pardo, Mercedes, Chen, Liangliang, Wu, Guangming, Zhu, Zhexin, Yu, Yong, Yu, Lu, Choudhary, Jyoti, Nichols, Jennifer, Parast, Mana M., Greber, Boris, Sahlén, Pelin, Plath, Kathrin
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486830/
https://ncbi.nlm.nih.gov/pubmed/30609396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.12.001
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