4-Chloropropofol enhances chloride currents in human hyperekplexic and artificial mutated glycine receptors

BACKGROUND: The mammalian neurological disorder hereditary hyperekplexia can be attributed to various mutations of strychnine sensitive glycine receptors. The clinical symptoms of “startle disease” predominantly occur in the newborn leading to convulsive hypertonia and an exaggerated startle respons...

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Detalhes bibliográficos
Main Authors: de la Roche, Jeanne, Leuwer, Martin, Krampfl, Klaus, Haeseler, Gertrud, Dengler, Reinhard, Buchholz, Vanessa, Ahrens, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517478/
https://ncbi.nlm.nih.gov/pubmed/23006332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-12-104
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