4-Chloropropofol enhances chloride currents in human hyperekplexic and artificial mutated glycine receptors

BACKGROUND: The mammalian neurological disorder hereditary hyperekplexia can be attributed to various mutations of strychnine sensitive glycine receptors. The clinical symptoms of “startle disease” predominantly occur in the newborn leading to convulsive hypertonia and an exaggerated startle respons...

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Hlavní autoři: de la Roche, Jeanne, Leuwer, Martin, Krampfl, Klaus, Haeseler, Gertrud, Dengler, Reinhard, Buchholz, Vanessa, Ahrens, Jörg
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517478/
https://ncbi.nlm.nih.gov/pubmed/23006332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-12-104
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