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Selection, synthesis, and anti-inflammatory evaluation of the arylidene malonate derivatives as TLR4 signaling inhibitors

Inhibition of TLR4 signaling is an important therapeutic strategy for intervention in the etiology of several pro-inflammatory diseases. There has been intensive research in recent years aiming to explore this strategy, and identify small molecule inhibitors of the TLR4 pathway. However, the recent...

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Detalles Bibliográficos
Main Authors: Zhang, Shuting, Cheng, Kui, Wang, Xiaohui, Yin, Hang
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517184/
https://ncbi.nlm.nih.gov/pubmed/22985959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.08.022
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