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Lck regulates IL-10 expression in memory-like Th1 cells
The Src family kinase Lck is thought to facilitate Th2 differentiation; however, its role in Th1 cells has not been well explored. Using mice that lack Lck in mature T cells, we find that lck(−/−) Th1 skewed cells have normal expression of T-bet and produce IFN-γ at WT levels. However, there is a 3-...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3517127/ https://ncbi.nlm.nih.gov/pubmed/21061443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040699 |
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