c-Maf Regulates IL-10 Expression during Th17 Polarization

IL-10 production by Th17 cells is critical for limiting autoimmunity and inflammatory responses. Gene array analysis on Stat6 and T-bet double-deficient Th17 cells identified the Th2 transcription factor c-Maf to be synergistically up-regulated by IL-6 plus TGFβ and associated with Th17 IL-10 produc...

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Detalhes bibliográficos
Main Authors: Xu, Jiangnan, Yang, Yu, Qiu, Guixing, Lal, Girdhari, Wu, Zhihong, Levy, David E., Ochando, Jordi C., Bromberg, Jonathan S., Ding, Yaozhong
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834209/
https://ncbi.nlm.nih.gov/pubmed/19414776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900123
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