IL-10 from marginal zone precursor B cells controls the differentiation of Th17, Tfh and Tfr cells in transplantation tolerance

B cells are known to control CD4 T cell differentiation in secondary lymphoid tissues. We hypothesized that IL-10 expression by marginal zone precursor (MZP) regulatory B cells controls the differentiation and positioning of effector and regulatory T cells during tolerization. Costimulatory blockade...

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Detalhes bibliográficos
Publicado no:Immunol Lett
Main Authors: Lal, Girdhari, Kulkarni, Neeraja, Nakayama, Yumi, Singh, Amit K., Sethi, Apoorva, Burrell, Bryna E, Brinkman, C. Colin, Iwami, Daiki, Zhang, Tianshu, Hehlgans, Thomas, Bromberg, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740190/
https://ncbi.nlm.nih.gov/pubmed/26772435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2016.01.002
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