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IL-10 from marginal zone precursor B cell subset is required for costimulatory blockade induced transplantation tolerance
BACKGROUND: Blocking CD40-CD40L costimulatory signals induces transplantation tolerance. While B cell depletion prevents alloantibody formation, non-humoral functions of B cells in tolerance have not been well characterized. We investigated whether specific subsets of B cell or B cell derived IL-10...
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| Udgivet i: | Transplantation |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4551603/ https://ncbi.nlm.nih.gov/pubmed/25839706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000000718 |
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