The p53-induced Gene Ei24 Is an Essential Component of the Basal Autophagy Pathway

Ei24 is a DNA damage response gene involved in growth suppression and apoptosis. The physiological function of Ei24, however, is poorly understood. Here we generated conditional knock-out mice of Ei24 and demonstrated that EI24 is an essential component of the basal autophagy pathway. Mice with neur...

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Autori principali: Zhao, Yan G., Zhao, Hongyu, Miao, Lin, Wang, Li, Sun, Fei, Zhang, Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516751/
https://ncbi.nlm.nih.gov/pubmed/23074225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.415968
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