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TRIM56 Is an Essential Component of the TLR3 Antiviral Signaling Pathway

Members of the tripartite motif (TRIM) proteins are being recognized as important regulators of host innate immunity. However, specific TRIMs that contribute to TLR3-mediated antiviral defense have not been identified. We show here that TRIM56 is a positive regulator of TLR3 signaling. Overexpressio...

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Библиографические подробности
Главные авторы: Shen, Yang, Li, Nan L., Wang, Jie, Liu, Baoming, Lester, Sandra, Li, Kui
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476306/
https://ncbi.nlm.nih.gov/pubmed/22948160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.397075
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