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TRIM56 Is an Essential Component of the TLR3 Antiviral Signaling Pathway

Members of the tripartite motif (TRIM) proteins are being recognized as important regulators of host innate immunity. However, specific TRIMs that contribute to TLR3-mediated antiviral defense have not been identified. We show here that TRIM56 is a positive regulator of TLR3 signaling. Overexpressio...

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Detalhes bibliográficos
Main Authors: Shen, Yang, Li, Nan L., Wang, Jie, Liu, Baoming, Lester, Sandra, Li, Kui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476306/
https://ncbi.nlm.nih.gov/pubmed/22948160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.397075
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