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TRIM56 Is an Essential Component of the TLR3 Antiviral Signaling Pathway

Members of the tripartite motif (TRIM) proteins are being recognized as important regulators of host innate immunity. However, specific TRIMs that contribute to TLR3-mediated antiviral defense have not been identified. We show here that TRIM56 is a positive regulator of TLR3 signaling. Overexpressio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shen, Yang, Li, Nan L., Wang, Jie, Liu, Baoming, Lester, Sandra, Li, Kui
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476306/
https://ncbi.nlm.nih.gov/pubmed/22948160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.397075
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