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TRIM56 Is an Essential Component of the TLR3 Antiviral Signaling Pathway

Members of the tripartite motif (TRIM) proteins are being recognized as important regulators of host innate immunity. However, specific TRIMs that contribute to TLR3-mediated antiviral defense have not been identified. We show here that TRIM56 is a positive regulator of TLR3 signaling. Overexpressio...

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Autores principales: Shen, Yang, Li, Nan L., Wang, Jie, Liu, Baoming, Lester, Sandra, Li, Kui
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476306/
https://ncbi.nlm.nih.gov/pubmed/22948160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.397075
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