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The p53-induced Gene Ei24 Is an Essential Component of the Basal Autophagy Pathway
Ei24 is a DNA damage response gene involved in growth suppression and apoptosis. The physiological function of Ei24, however, is poorly understood. Here we generated conditional knock-out mice of Ei24 and demonstrated that EI24 is an essential component of the basal autophagy pathway. Mice with neur...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3516751/ https://ncbi.nlm.nih.gov/pubmed/23074225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.415968 |
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