Amphiregulin, an Epidermal Growth Factor Receptor Ligand, Plays an Essential Role in the Pathogenesis of Transforming Growth Factor-β-induced Pulmonary Fibrosis

Dysregulated amphiregulin (AR) expression and EGR receptor (EGFR) activation have been described in animal models of pulmonary fibrosis and in patients with idiopathic pulmonary fibrosis. However, the exact role of AR in the pathogenesis of pulmonary fibrosis has not been clearly defined. Here, we s...

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Hoofdauteurs: Zhou, Yang, Lee, Jae-Young, Lee, Chang-Min, Cho, Won-Kyung, Kang, Min-Jong, Koff, Jonathan L., Yoon, Pyeong-Oh, Chae, Jeiwook, Park, Han-Oh, Elias, Jack A., Lee, Chun Geun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2012
Onderwerpen:
Molecular Bases of Disease
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516745/
https://ncbi.nlm.nih.gov/pubmed/23086930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356824
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