Amphiregulin, an Epidermal Growth Factor Receptor Ligand, Plays an Essential Role in the Pathogenesis of Transforming Growth Factor-β-induced Pulmonary Fibrosis

Dysregulated amphiregulin (AR) expression and EGR receptor (EGFR) activation have been described in animal models of pulmonary fibrosis and in patients with idiopathic pulmonary fibrosis. However, the exact role of AR in the pathogenesis of pulmonary fibrosis has not been clearly defined. Here, we s...

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Detalhes bibliográficos
Main Authors: Zhou, Yang, Lee, Jae-Young, Lee, Chang-Min, Cho, Won-Kyung, Kang, Min-Jong, Koff, Jonathan L., Yoon, Pyeong-Oh, Chae, Jeiwook, Park, Han-Oh, Elias, Jack A., Lee, Chun Geun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516745/
https://ncbi.nlm.nih.gov/pubmed/23086930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356824
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