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Human Mismatch Repair Protein hMutLα Is Required to Repair Short Slipped-DNAs of Trinucleotide Repeats

Mismatch repair (MMR) is required for proper maintenance of the genome by protecting against mutations. The mismatch repair system has also been implicated as a driver of certain mutations, including disease-associated trinucleotide repeat instability. We recently revealed a requirement of hMutSβ in...

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Main Authors: Panigrahi, Gagan B., Slean, Meghan M., Simard, Jodie P., Pearson, Christopher E.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516732/
https://ncbi.nlm.nih.gov/pubmed/23086927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.420398
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