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Absence of MutSbeta leads to the formation of slipped-DNA for CTG/CAG contractions at primate replication forks
Typically disease-causing CAG/CTG repeats expand, but rare affected families can display high levels of contraction of the expanded repeat amongst offspring. Understanding instability is important since arresting expansions or enhancing contractions could be clinically beneficial. The MutSβ mismatch...
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| Publicado no: | DNA Repair (Amst) |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5096786/ https://ncbi.nlm.nih.gov/pubmed/27155933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.04.002 |
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