STAT3 Protein Up-regulates Gα-interacting Vesicle-associated Protein (GIV)/Girdin Expression, and GIV Enhances STAT3 Activation in a Positive Feedback Loop during Wound Healing and Tumor Invasion/Metastasis

Gα-interacting vesicle-associated protein (GIV) is a guanine nucleotide exchange factor that modulates key signaling pathways during a diverse set of biological processes, e.g. wound healing, macrophage chemotaxis, tumor angiogenesis, vascular repair, and cancer invasion/metastasis. We recently demo...

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Hlavní autoři: Dunkel, Ying, Ong, Andrew, Notani, Dimple, Mittal, Yash, Lam, Michael, Mi, Xiaoyi, Ghosh, Pradipta
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516717/
https://ncbi.nlm.nih.gov/pubmed/23066027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.390781
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