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Chronic Pulsatile Hyperglycemia Reduces Insulin Secretion and Increases Accumulation of Reactive Oxygen Species in Fetal Sheep Islets

Children from diabetic pregnancies have a greater incidence of Type 2 diabetes. Our objective was to determine if exposure to mild-moderate hyperglycemia, modeling managed diabetic pregnancies, affects fetal β-cell function. In sheep fetuses β-cell responsiveness was examined after two weeks of sust...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Green, Alice S., Chen, Xiaochuan, Macko, Antoni R., Anderson, Miranda J., Kelly, Amy C., Hart, Nathaniel J., Lynch, Ronald M., Limesand, Sean W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516619/
https://ncbi.nlm.nih.gov/pubmed/22182602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-11-0300
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