Clofazimine Modulates the Expression of Lipid Metabolism Proteins in Mycobacterium leprae-Infected Macrophages

Mycobacterium leprae (M. leprae) lives and replicates within macrophages in a foamy, lipid-laden phagosome. The lipids provide essential nutrition for the mycobacteria, and M. leprae infection modulates expression of important host proteins related to lipid metabolism. Thus, M. leprae infection incr...

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Detalhes bibliográficos
Main Authors: Degang, Yang, Akama, Takeshi, Hara, Takeshi, Tanigawa, Kazunari, Ishido, Yuko, Gidoh, Masaichi, Makino, Masahiko, Ishii, Norihisa, Suzuki, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516583/
https://ncbi.nlm.nih.gov/pubmed/23236531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001936
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