An Integrated In Silico Approach to Design Specific Inhibitors Targeting Human Poly(A)-Specific Ribonuclease

Poly(A)-specific ribonuclease (PARN) is an exoribonuclease/deadenylase that degrades 3′-end poly(A) tails in almost all eukaryotic organisms. Much of the biochemical and structural information on PARN comes from the human enzyme. However, the existence of PARN all along the eukaryotic evolutionary l...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Vlachakis, Dimitrios, Pavlopoulou, Athanasia, Tsiliki, Georgia, Komiotis, Dimitri, Stathopoulos, Constantinos, Balatsos, Nikolaos A. A., Kossida, Sophia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516499/
https://ncbi.nlm.nih.gov/pubmed/23236441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051113
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi