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Sonic hedgehog regulates presynaptic terminal size, ultrastructure and function in hippocampal neurons

Sonic hedgehog (Shh) signaling is essential to the patterning of the embryonic neural tube, but its presence and function in the postmitotic differentiated neurons in the brain remain largely uncharacterized. We recently showed that Shh and its signaling components, Patched and Smoothened, are expre...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mitchell, Nicholas, Petralia, Ronald S., Currier, Duane G., Wang, Ya-Xian, Kim, Alvin, Mattson, Mark P., Yao, Pamela J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516435/
https://ncbi.nlm.nih.gov/pubmed/22641692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.105080
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