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Sonic hedgehog regulates presynaptic terminal size, ultrastructure and function in hippocampal neurons

Sonic hedgehog (Shh) signaling is essential to the patterning of the embryonic neural tube, but its presence and function in the postmitotic differentiated neurons in the brain remain largely uncharacterized. We recently showed that Shh and its signaling components, Patched and Smoothened, are expre...

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Detalhes bibliográficos
Main Authors: Mitchell, Nicholas, Petralia, Ronald S., Currier, Duane G., Wang, Ya-Xian, Kim, Alvin, Mattson, Mark P., Yao, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516435/
https://ncbi.nlm.nih.gov/pubmed/22641692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.105080
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