Impact of Prefrontal Cortex in Nicotine-Induced Excitation of Ventral Tegmental Area Dopamine Neurons in Anesthetized Rats

Systemic administration of nicotine increases dopaminergic (DA) neuron firing in the ventral tegmental area (VTA), which is thought to underlie nicotine reward. Here, we report that the medial prefrontal cortex (mPFC) plays a critical role in nicotine-induced excitation of VTA DA neurons. In chloral...

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Main Authors: Zhang, Die, Gao, Ming, Xu, Dan, Shi, Wei-Xing, Gutkin, Boris S., Steffensen, Scott C., Lukas, Ronald J., Wu, Jie
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2012
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516404/
https://ncbi.nlm.nih.gov/pubmed/22956827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5411-11.2012
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