Impact of Prefrontal Cortex in Nicotine-Induced Excitation of Ventral Tegmental Area Dopamine Neurons in Anesthetized Rats

Systemic administration of nicotine increases dopaminergic (DA) neuron firing in the ventral tegmental area (VTA), which is thought to underlie nicotine reward. Here, we report that the medial prefrontal cortex (mPFC) plays a critical role in nicotine-induced excitation of VTA DA neurons. In chloral...

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Detalhes bibliográficos
Main Authors: Zhang, Die, Gao, Ming, Xu, Dan, Shi, Wei-Xing, Gutkin, Boris S., Steffensen, Scott C., Lukas, Ronald J., Wu, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516404/
https://ncbi.nlm.nih.gov/pubmed/22956827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5411-11.2012
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