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A Screen to Identify cellular Modulators of Soluble Levels of an Amyotrophic Lateral Sclerosis (ALS)–causing Mutant SOD1

The molecular pathology of many protein misfolding, toxic gain-of-function diseases, such as amyotrophic lateral sclerosis (ALS), is not well understood. Although protein misfolding and aggregation are common themes in these diseases, efforts to identify cellular factors that regulate this process i...

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Detalhes bibliográficos
Main Authors: SOMALINGA, BALAJEE R., MILLER, GREGORY A., MALIK, HIBA T., WIGLEY, W. CHRISTIAN, THOMAS, PHILIP J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516231/
https://ncbi.nlm.nih.gov/pubmed/21875953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057111418505
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