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Radioprobing the Conformation of DNA in a p53-DNA Complex

PURPOSE: The frequency of DNA strand breaks produced by the decay of Auger electron-emitting radionuclides is inversely proportional to the distance of DNA nucleotides from the decay site; and thus is very sensitive to changes in the local conformation of the DNA. Analysis of the frequency of DNA br...

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Main Authors: Karamychev, V. N., Wang, D., Mazur, S., Appella, E., Neumann, R. D., Zhurkin, V. B., Panyutin, I. G.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515845/
https://ncbi.nlm.nih.gov/pubmed/22640875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/09553002.2012.698030
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