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Iodine-125 Radioprobing of Intramolecular Quadruplex Conformation of Human Telomeric DNA in the Presence of Cationic Porphyrin TMPyP4

PURPOSE: A repeated, non-coding, DNA sequence d(TTAGGG)(n) is present in the telomeric ends of all human chromosomes. These repeats can adopt multiple inter- and intra-molecular non-B-DNA conformations that may play an important role in biological processes. We applied (125)I -radioprobing to assess...

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Main Authors: Gaynutdinov, Timur I., Neumann, Ronald D., Panyutin, Igor G.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2599904/
https://ncbi.nlm.nih.gov/pubmed/19061122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09553000802415747
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