Basolateral chloride loading by the anion exchanger type 2: role in fluid secretion by the human airway epithelial cell line Calu-3

Anion exchanger type 2 (AE2 or SLC4A2) is an electroneutral Cl(−)/HCO(3)(−) exchanger expressed at the basolateral membrane of many epithelia. It is thought to participate in fluid secretion by airway epithelia. However, the role of AE2 in fluid secretion remains uncertain, due to the lack of specif...

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Bibliographic Details
Main Authors: Huang, Junwei, Shan, Jiajie, Kim, Dusik, Liao, Jie, Evagelidis, Alexandra, Alper, Seth L, Hanrahan, John W
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2012
Subjects:
Molecular and Cellular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515820/
https://ncbi.nlm.nih.gov/pubmed/22802585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.236919
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