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Transcriptional activation of transposable elements in mouse zygotes is independent of Tet3-mediated 5-methylcytosine oxidation

The methylation state of the paternal genome is rapidly reprogrammed shortly after fertilization. Recent studies have revealed that loss of 5-methylcytosine (5mC) in zygotes correlates with appearance of 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). This proc...

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Detalhes bibliográficos
Main Authors: Inoue, Azusa, Matoba, Shogo, Zhang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515759/
https://ncbi.nlm.nih.gov/pubmed/23184059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.160
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