Cardiac Ankyrin Repeat Protein Attenuates Cardiac Hypertrophy by Inhibition of ERK1/2 and TGF-β Signaling Pathways

AIMS: It has been reported that cardiac ankyrin repeat protein is associated with heart development and diseases. This study is aimed to investigate the role of CARP in heart hypertrophy in vivo. METHODS AND RESULTS: We generated a cardiac-specific CARP-overexpressing transgenic mouse. Although such...

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Main Authors: Song, Yao, Xu, Jialin, Li, Yanfeng, Jia, Chunshi, Ma, Xiaowei, Zhang, Lei, Xie, Xiaojie, Zhang, Yong, Gao, Xiang, Zhang, Youyi, Zhu, Dahai
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515619/
https://ncbi.nlm.nih.gov/pubmed/23227174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050436
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