Cardiac Ankyrin Repeat Protein Attenuates Cardiac Hypertrophy by Inhibition of ERK1/2 and TGF-β Signaling Pathways

AIMS: It has been reported that cardiac ankyrin repeat protein is associated with heart development and diseases. This study is aimed to investigate the role of CARP in heart hypertrophy in vivo. METHODS AND RESULTS: We generated a cardiac-specific CARP-overexpressing transgenic mouse. Although such...

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Detalhes bibliográficos
Main Authors: Song, Yao, Xu, Jialin, Li, Yanfeng, Jia, Chunshi, Ma, Xiaowei, Zhang, Lei, Xie, Xiaojie, Zhang, Yong, Gao, Xiang, Zhang, Youyi, Zhu, Dahai
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515619/
https://ncbi.nlm.nih.gov/pubmed/23227174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050436
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