CTGF Increases IL-6 Expression in Human Synovial Fibroblasts through Integrin-Dependent Signaling Pathway

BACKGROUND: Connective tissue growth factor (CTGF; also known as CCN2) is an inflammatory mediator, and shows elevated levels in regions of severe injury and inflammatory diseases. CTGF is abundantly expressed in osteoarthritis (OA). However, the relationship between CTGF and IL-6 in OA synovial fib...

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Bibliografische gegevens
Hoofdauteurs: Liu, Shan-Chi, Hsu, Chin-Jung, Chen, Hsien-Te, Tsou, Hsi-Kai, Chuang, Show-Mei, Tang, Chih-Hsin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515445/
https://ncbi.nlm.nih.gov/pubmed/23227240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051097
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